Which work by Eugene O'Neill is a semi-autobiographical drama about addiction and family dysfunction?

"Long Day's Journey Into Night" is indeed the correct answer to this question. This play is a poignant exploration of O'Neill's own family life and struggles, particularly highlighting themes of addiction, illness, and the complexities of familial relationships. The characters in the play mirror O'Neill's own family members, with the protagonist, James Tyrone, representing O'Neill's father, who was a successful actor but also battled alcohol addiction.

The interplay of addiction and family dysfunction is depicted through the interactions among the Tyrones, illustrating the cycles of dependency and the impact of past traumas on present relationships. The emotional depth and honesty in the portrayal of each character’s flaws and desires reflect O'Neill's own experiences, making this work semi-autobiographical in nature.

The other options, while notable works, do not share the same level of autobiographical connection with addiction and family issues as "Long Day's Journey Into Night." "The Iceman Cometh" deals with themes of disillusionment and unreality among a group of down-and-out characters in a bar, but it does not focus specifically on family dynamics. "Who's Afraid of Virginia Woolf?" is a dramatic exploration of a troubled marriage, and "Waiting